GM Crop Database

Database Product Description

TC1507 x MON810 x NK603 (DAS-Ø15Ø7-1xMON-ØØ81Ø-6xMON-ØØ6Ø3-6)
Host Organism
Zea mays (Maize)
Trait

Herbicide tolerant, glufosinate ammonium; Herbicide tolerant,glyphosate; Insect resistant, Lepidoptera.

Trait Introduction
Traditional plant breeding and selection
Proposed Use

Production for human consumption and livestock feed.

Product Developer
DuPont Pioneer

Summary of Regulatory Approvals

Country Food Feed Environment Notes
Argentina 2013 2013 2013
Brazil 2011 2011 2011
Canada 2011 2011 View
Colombia 2012 2012 2011
Japan 2011 2011 2011
Korea 2010
Mexico 2010 2010
Philippines 2012 2012 2014
South Africa 2014 2014 2014
Taiwan 2011

Introduction Expand

This stacked maize hybrid is a product of traditional plant breeding, and is therefore not automatically subject to regulation in all countries, unlike transgenic plants resulting from recombinant-DNA technologies. The approvals table above does not include entries from these countries. Other countries may request notification in advance of the release of a stacked hybrid, or may request information to conduct an environmental and food safety assessment, and these countries’ decisions are reflected in the approvals table.

Summary of Introduced Genetic Elements Expand

Code Name Type Promoter, other Terminator Copies Form
cry1Fa2 cry1F delta-endotoxin IR ubiquitin (ubi) ZM (Zea mays) promoter and the first exon and intron 3' poly-adenylation signal from ORF25 (Agrobacterium tumefaciens) 1 functional; 1-2 partial; Altered coding sequence for optimal expression in plant cells.
pat phosphinothricin N-acetyltransferase HT CaMV 35S CaMV 35S 3' polyadenylation signal 1 functional;
cry1Ab Cry1Ab delta-endotoxin (Btk HD-1) IR enhanced CaMV 35S, maize HSP70 intron None. Lost through 3' truncation during integration 1 Truncated
CP4 epsps 5-enolpyruvyl shikimate-3-phosphate synthase HT P-ract1/ract1 intron containing rice actin 1 promoter, transcription start site chloroplast transit peptide from A. thaliana EPSPS gene (CTP2) A. tumefaciens nopaline synthase (nos) 3'-untranslated region 1 CP4 EPSPS gene modified for plant-preferred codons
CP4 epsps 5-enolpyruvyl shikimate-3-phosphate synthase HT enhanced CaMV 35S, maize HSP70 intron chloroplast transit peptide from A. thaliana EPSPS gene (CTP2) A. tumefaciens nopaline synthase (nos) 3'-untranslated region 1 CP4 EPSPS gene modified for plant-preferred codons

Characteristics of Zea mays (Maize) Expand

Center of Origin Reproduction Toxins Allergenicity

Mesoamerican region, now Mexico and Central America

Cross-pollination via wind-borne pollen is limited, pollen viability is about 30 minutes. Hybridization reported with teosinte species and rarely with members of the genus Tripsacum.

No endogenous toxins or significant levels of antinutritional factors.

Although some reported cases of maize allergy, protein(s) responsible have not been identified.

Donor Organism Characteristics Expand

Latin Name Gene Pathogenicity
Bacillus thuringiensis var. aizawai cry1F While target insects are susceptible to oral doses of Bt proteins, no evidence of toxic effects in laboratory mammals or birds.
Streptomyces viridochromogenes pat

S. viridochromogenes is ubiquitous in the soil. It exhibits very slight antimicrobial activity, is inhibited by streptomycin, and there have been no reports of adverse affects on humans, animals, or plants.

Bacillus thuringiensis subsp. kurstaki EC2.4.2.19

While target insects are susceptible to oral doses of Bt proteins, no evidence of toxic effects in laboratory mammals or birds given up to 10 µg protein/g body weight.

Agrobacterium tumefaciens strain CP4 CP4 epsps

Agrobacterium tumefaciens is a common soil bacterium that is responsible for causing crown gall disease in susceptible plants. There have been no reports of adverse effects on humans or animals.

Modification Method Expand

Coming soon. 

Characteristics of the Modification Expand

Coming soon.

Environmental Safety Considerations Expand

Coming soon. 

Food and/or Feed Safety Considerations Expand

Coming soon.

Links to Further Information Expand

Argentina Secretariat of Agriculture, Livestock and Fisheries Brazil Ministry of Science and Technology - MCT The National Biosafety Technical - CTNBio Executive Secretary Colombian Agricultural Institute ICA Colombian Agricultural Institute Japan (MAFF) Mexican Health Secretary Federal Commission for the Protection against Sanitary Risk Ministerio de Salud Proteccion Social

This record was last modified on Tuesday, March 1, 2016