GM Crop Database

Database Product Description

MON88701 (MON-887Ø1-3)
Host Organism
Gossypium hirsutum (Cotton)
Multiple Herbicide Tolerance
Trait Introduction
Agrobacterium tumefaciens-mediated plant transformation.
Proposed Use

Production for human consumption and livestock feed.

Product Developer
Monsanto Company

Summary of Regulatory Approvals

Country Food Feed Environment Notes
Australia 2014
Canada 2014 2014
Colombia 2016
Japan 2014 2015
Korea 2015 2015
Mexico 2014 2014
New Zealand 2014
Taiwan 2016
United States 2013 2013 2015

Introduction Expand

Coming soon.

Summary of Introduced Genetic Elements Expand

Code Name Type Promoter, other Terminator Copies Form
dmo dicamba mono-oxygenase HT



bar Phosphinothricin acetyltransferase HT




Characteristics of Gossypium hirsutum (Cotton) Expand

Center of Origin Reproduction Toxins Allergenicity

Believed to originate in Meso-America (Peruvian-Ecuadorian-Bolivian region).

Generally self-pollinating, but can be cross-pollinating in the presence of suitable insect pollinators (bees). In the U.S., compatible species include G. hirsutum, G. barbadense, and G. tomentosum.

Gossypol in cottonseed meal.

Cotton is not considered to be allergenic, although there are rare, anecdotal reports of allergic reactions in the literature.

Donor Organism Characteristics Expand

Latin Name Gene Pathogenicity
Stenotrophomonas maltophilia 5AT

The dmo gene is derived from the bacterium Stenotrophomonas maltophilia (Palleroni and Bradbury, 1993). S. maltophilia is an aerobic, ubiquitous environmental gram negative bacterium commonly present in aquatic environments, soil, and plants. S. maltophilia is ubiquitously associated with plants and has been isolated from the rhizosphere of wheat, maize, grasses, beet, cucumber, chicory, potato, strawberry, sugarcane, and rapeseed (Berg et al., 1996; Berg et al., 1999; Berg et al., 2002; Denton et

al., 1998; Echemendia, 2007; Juhnke and des Jardin, 1989; Juhnke et al., 1987; Lambert et al., 1987). S. maltophilia was isolated from cotton seed, bean pods, and coffee (Nunes and de Melo, 2006; Swings et al., 1983), thus, S. maltophilia can be found in a variety offoods and feeds.

It is also widespread in the home environment and can be found around dishwashers, sponges, toothbrushes, flowers, plants, fruits, vegetables, frozen fish, milk, and poultry (Ryan et al., 2009). Strains of S. maltophilia have been found in the transient flora of hospitalized patients as a commensal organism (Echemendia, 2007). Infections caused by S. maltophilia are extremely uncommon (Cunha, 2006), and S. maltophilia can be found in healthy individuals without causing any harm to human health (Denton et al., 1998). Similar to the indigenous bacteria of the gastrointestinal tract, S. maltophilia can be an opportunistic pathogen (Berg, 1996). As such, S. maltophilia is of low virulence in immuno-compromised patients where a series of factors must occur for colonization by S. maltophilia on humans (Ryan et al., 2009). 

Streptomyces hygroscopicus bar S. hygroscopicus is ubiquitous in the soil and there have been no reports of adverse affects on humans, animals, or plants.

Modification Method Expand

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Characteristics of the Modification Expand

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Environmental Safety Considerations Expand

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Food and/or Feed Safety Considerations Expand

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Links to Further Information Expand

This record was last modified on Wednesday, January 4, 2017