GM Crop Database

Database Product Description

DP-305423-1 x GTS 40-3-2 (DP-3Ø5423-1xMON-Ø4Ø32-6)
Host Organism
Glycine max (Soybean)
Trait

Multiple Herbicide Tolerance, Product Quality

Trait Introduction
Traditional plant breeding and selection
Proposed Use

Production for human consumption and livestock feed.

Product Developer
DuPont Pioneer

Summary of Regulatory Approvals

Country Food Feed Environment Notes
Argentina 2015 2015 2015
Japan 2012 2012 2012
Korea 2011 2011
Mexico 2010 2010
Philippines 2014 2014
South Africa 2011 2011
Taiwan 2012 2012

Introduction Expand

Coming soon.

Summary of Introduced Genetic Elements Expand

Code Name Type Promoter, other Terminator Copies Form
gm-fad2-1 delta(12)-fatty acid dehydrogenase PQ

KTi3 promoter region of Kunitz trypsin inhibitor 3 gene derived from soybean to induce transcription

KTi3 terminator region of Kunitz trypsin inhibitor 3 gene derived from soybean to terminate transcription

epsps 5-enol-pyruvylshikimate-3-phosphate synthase HT

35S promoter of cauliflower mosaic virus (CaMV). Has a duplication enhancer region. Involved in the constitutive expression of the target gene in all tissues

NOS 3' untranslated region of nopaline synthase (NOS) gene derived from T-DNA of Agrobacterium tumefaciens

5-enol-pyruvyl-shikimate-3-phosphate synthase gene derived from Agrobacterium strain CP4

gm-hra acetolactate synthase HT

SAMS constitutive expression promoter region of S-adenosyl-L-methionine synthetase (SAMS) gene derived from soybean

als terminator region of als gene derived from soybean to terminate transcription

Soy acetolactate synthase (als), conferring herbicide resistance. Pro178 in the endogenous gene has been substituted with Ala and Trp555 was substituted with Leu. In addition, 5 amino acids (Met-Pro-His-Asn-Thr) were added in the N-terminal region.

hyg E. coli hygromycin B phosphotransferase SM

T7 promoter region derived from coliform bacteriophage T7 genome

T7 A terminator region derived from coliform bacteriophage T7 genome

Antibiotic hygromycin-resistant gene derived from Escherichia coli (E. coli) (GenBank Accession No. K01193)

Characteristics of Glycine max (Soybean) Expand

Center of Origin Reproduction Toxins Allergenicity

Southeast Asia; wild soybean species endemic in China, Korea, Japan, Taiwan.

Self-polinated; rarely displays any dormancy characteristics; does not compete well with other cultivated plants.

Raw soybeans contain trypsin inhibitors, which are toxin when eaten.

Soy allergies are common, and eating soy products can cause rashes and swelling of the skin in sensitive individuals.

Donor Organism Characteristics Expand

Latin Name Gene Pathogenicity
Glycine max gm-fad2-1

There is no published evidence that soybean is a human or animal pathogen.

Agrobacterium tumefaciens strain CP4 CP4 epsps

Agrobacterium tumefaciens is a common soil bacterium that is responsible for causing crown gall disease in susceptible plants. There have been no reports of adverse effects on humans or animals.

Glycine max gm-fad2-1

There is no published evidence that soybean is a human or animal pathogen.

Escherichia coli (K-12) hyg

Escherichia coli is one of a number of microorganisms which are normal inhabitants of the colons of virtually all warm-blooded mammals. Ecoli belongs to the taxonomic family known asEnterobacteriaceae, which is one of the best-defined groups of bacteria. The strain Ecoli K-12 is a debilitated strain which does not normally colonize the human intestine. It has also been shown to survive poorly in the environment, has a history of safe commercial use, and is not known to have adverse effects on microorganisms or plants. 

Modification Method Expand

Coming soon.

Characteristics of the Modification Expand

Coming soon.

Environmental Safety Considerations Expand

Coming soon.

Food and/or Feed Safety Considerations Expand

Coming soon.

Links to Further Information Expand


This record was last modified on Monday, June 20, 2016