GM Crop Database

Database Product Description

DAS-44406-6 (DAS-444Ø6-6)
Host Organism
Glycine max (Soybean)
Trait

Herbicide tolerant, 2,4-D; Herbicide tolerant, glufosinate ammonium; Herbicide tolerant, glyphosate.

Trait Introduction
Agrobacterium tumefaciens-mediated plant transformation.
Proposed Use

Production for human consumption and livestock feed.

Product Developer
DOW AgroSciences LLC

Summary of Regulatory Approvals

Country Food Feed Environment Notes
Argentina 2015 2015 2015
Australia 2013
Canada 2013 2013 2013
Colombia 2016
Japan 2014 2015 2015
Korea 2014 2014
Mexico 2014 2014
New Zealand 2013
South Africa 2013 2013
Taiwan 2014 2014 View
United States 2013 2013 2014
Uruguay 2014

Introduction Expand

Coming soon.

Summary of Introduced Genetic Elements Expand

Code Name Type Promoter, other Terminator Copies Form
aad-12 Aryloxyalkanoate dioxygenase HT

AtUbi10 promoter

AtuORF23 3′ UTR

1

Plant-optimized version of an aryloxyalkanoate dioxygenase gene

epsps 5-enolpyruvylshikimate-3-phosphate synthase HT

Histone H4A748 promoter; Histone H3 Gene II intron 1; optimized transit peptide TPotp C

Histone H4A748 3′ UTR; RB7 matrix attachment region

1

Native 5-enolpyruvylshikimate-3-phosphate synthase gene from Zea mays with two mutations providing glyphosate tolerance

pat Phosphinothricin acetyltransferase HT

CsVMV promoter

AtuORF1 3′ UTR

1

Plant-optimized version of phosphinothricin acetyltransferase gene

Characteristics of Glycine max (Soybean) Expand

Center of Origin Reproduction Toxins Allergenicity

Southeast Asia; wild soybean species endemic in China, Korea, Japan, Taiwan.

Self-polinated; rarely displays any dormancy characteristics; does not compete well with other cultivated plants.

Raw soybeans contain trypsin inhibitors, which are toxin when eaten.

Soy allergies are common, and eating soy products can cause rashes and swelling of the skin in sensitive individuals.

Donor Organism Characteristics Expand

Latin Name Gene Pathogenicity
Delftia acidovorans aad

Delftia acidovorans is a non-glucose-fermenting, gram-negative, non-spore-forming rod present in soil, fresh water, activated sludge, and clinical specimens.  It can be used to transform ferulic acid into vanillin and related flavor metabolites and has been used in the food processing industry.  D. acidovorans is an ubiquitous gram-negative bacterium not generally considered to be pathogenic, although rarely it is found associated with human infections.

Zea mays epsps

Not applicable.

Streptomyces viridochromogenes pat

S. viridochromogenes is ubiquitous in the soil. It exhibits very slight antimicrobial activity, is inhibited by streptomycin, and there have been no reports of adverse affects on humans, animals, or plants.

Modification Method Expand

Coming soon.

Characteristics of the Modification Expand

Coming soon.

Environmental Safety Considerations Expand

Coming soon.

Food and/or Feed Safety Considerations Expand

Coming soon.

Links to Further Information Expand

Argentina Ministry of Agriculture, Livestock and Fisheries Japan Food Commission Korean Ministry of Food and Drug Safety Uruguay Gabinete Nacional de Bioseguridad (GNBio)

This record was last modified on Thursday, August 18, 2016