GM Crop Database

Database Product Description

DAS-40278-9 (DAS-4Ø278-9)

Host Organism

Zea mays (Maize)

Trait

Herbicide tolerant, 2,4-D; Herbicide tolerant, aryloxyphenoxy-propionate herbicides

Trait Introduction

Direct DNA transfer system

Proposed Use

Production for human consumption and livestock feed.

Product Developer

DOW AgroSciences LLC

Summary of Regulatory Approvals

Introduction Expand

Coming soon.

Summary of Introduced Genetic Elements Expand

Code	Name	Type	Promoter, other	Terminator	Copies	Form
aad-1	aryloxyalkanoate dioxygenase	HT	ZmUbi1 (Zea mays)	ZmPer5 (Zea mays)		Codons were optimized for expression in plants

Characteristics of Zea mays (Maize) Expand

Center of Origin	Reproduction	Toxins	Allergenicity
Mesoamerican region, now Mexico and Central America	Cross-pollination via wind-borne pollen is limited, pollen viability is about 30 minutes. Hybridization reported with teosinte species and rarely with members of the genus Tripsacum.	No endogenous toxins or significant levels of antinutritional factors.	Although some reported cases of maize allergy, protein(s) responsible have not been identified.

Donor Organism Characteristics Expand

Latin Name	Gene	Pathogenicity
Sphingobium herbicidovorans	aad-1	S. herbicidovorans is a common soil bacterium, widespread in the environment. There have been no reports of adverse effects on humans or animals.

Modification Method Expand

Coming soon.

Characteristics of the Modification Expand

Coming soon.

Environmental Safety Considerations Expand

Coming soon.

Food and/or Feed Safety Considerations Expand

Coming soon.

Links to Further Information Expand

• Australia/New Zealand (FSANZ): Approval Report-Application A1042
  [PDF Size: 0.99M bytes]
• Canada (CFIA): Decision Document 2012-92 Determination of the Safety of Dow AgroSciences Canada Inc.'s Corn (Zea mays L.) Event DAS-40278-9
  [PDF Size: 156.55K bytes]
• Canada (Health Canada): Corn Producing Aryloxyalkanoate Dioxygenase-1 (AAD-1) - DAS-40278-9
  [PDF Size: 119.18K bytes]
• Colombia (MSPS): Por la cual se autoriza el uso de Maíz DAS 40278 (DAS-40278-9) como alimento o materia prima para la elaboración de alimentos de consumo humano
  [PDF Size: 370.44K bytes]
• United States (FDA): Biotechnology Consultation Note to the File BNF No. 000120
  [PDF Size: 241.18K bytes]
• United States (USDA): Determination of Nonregulated Status for Dow AgroSciences’ DAS-40278-9
  [PDF Size: 150.57K bytes]
• United States (USDA): Dow AgroSciences Petitions (09-233-01p, 09-349-01p, and 11-234-01p) for Determinations of Nonregulated Status for 2,4-D-Resistant Corn and Soybean Varieties; Final Environmental Impact Statement—August 2014
  [PDF Size: 3.51M bytes]
• United States (USDA): Petition for Determination of Nonregulated Status for Herbicide Tolerant DAS-40278-9 Corn
  [PDF Size: 6.95M bytes]
• United States (USDA): Plant Pest Risk Assessment for DAS-40278-9 Corn
  [PDF Size: 233.70K bytes]

Japan Ministry of the Environment

• Biological Diversity Risk Assessment Report for Maize tolerant to aryloxyalkanoate herbicide (Modified aad-1, Zea mays subsp. mays (L.) Iltis) (DAS40278, OECD UI: DAS-4Ø278-9)
  [PDF Size: 132.71K bytes]

MEXICAN FEDERAL DEPARTMENT OF HEALTH COMMISSION FOR PROTECTION AGAINST HEALTH RISKS

• SUMMARY OF SAFETY ASSESSMENT OF GMOS for Maize (Zea mays ) OECD identifier : DAS - 40278-9
  [PDF Size: 270.90K bytes]

This record was last modified on Friday, June 3, 2016