GM Crop Database

Database Product Description

Bt11 x DAS-59122 x MIR604 x TC1507-1 x GA21 (SYN-BTØ11-1 x DAS-59122-7 x SYN-IR6Ø4-5 x DAS-Ø15Ø7-1 x MON-ØØØ21-9)
Host Organism
Zea mays (Maize)
Trait

Herbicide tolerant, glufosinate ammonium; Herbicide tolerant, glyphosate; Insect resistant, Coleoptera; Insect resistant, Lepidoptera.

Trait Introduction
Traditional plant breeding and selection
Proposed Use

Production for human consumption and livestock feed.

Product Developer
Syngenta Seeds, Inc.

Summary of Regulatory Approvals

Country Food Feed Environment Notes
Colombia 2016
Japan 2011 2011 2011
Korea 2013 2011
Mexico 2011 2011
Philippines 2011 2011
South Africa 2014 2014
Taiwan 2012

Introduction Expand

Coming soon.

Summary of Introduced Genetic Elements Expand

Code Name Type Promoter, other Terminator Copies Form
cry1Ab Cry1Ab delta-endotoxin IR

35S promoter from Cauliflower Mosaic Virus; IVS6-ADH1 enhancer from Zea mays

NOS terminator from Agrobacterium tumefaciens

Sequence was modified for plant codon preference

cry1F Cry1F delta-endotoxin IR

UBIZM1(2) ubiquitin promoter from Zea mays

ORF25PolyA terminator from A. tumefaciens

cry34Ab1 Cry34Ab1 delta-endotoxin IR

UBI1ZM PRO ubiquitin promoter from Zea mays

PIN II TERM protease inhibitor terminator from Solanum tuberosum

cry35Ab1 Cry35Ab1 delta-endotoxin IR

TA Peroxidase PRO peroxidase promoter from Triticum aestivum

PIN II TERM protease inhibitor terminator from Solanum tuberosum

mcry3A Cry3A delta-endotoxin IR

MTL metallothionein promoter from Zea mays

NOS terminator from A. tumefaciens

pat Phosphinothricin acetyltransferase HT

35S promoter from Cauliflower Mosaic Virus; IVS6-ADH1 enhancer from Zea mays

NOS terminator from Agrobacterium tumefaciens

Sequence was modified for plant codon preference

pat Phosphinothricin acetyltransferase HT

35S PRO promoter from Cauliflower Mosaic Virus

35S TERM terminator from Cauliflower Mosaic Virus

pmi Phosphomannose isomerase SM

ZmUbiInt polyubiquitin promoter from Zea mays

NOS terminator from A. tumefaciens

epsps 5-enol-pyruvyl-shikimate-3-phospphate synthase HT

Act actin promoter from Oryza sativa; sssu+mssu RuBisCo transit peptides from Zea mays and Helianthus annuus

NOS terminator from A. tumefaciens

Characteristics of Zea mays (Maize) Expand

Center of Origin Reproduction Toxins Allergenicity

Mesoamerican region, now Mexico and Central America

Cross-pollination via wind-borne pollen is limited, pollen viability is about 30 minutes. Hybridization reported with teosinte species and rarely with members of the genus Tripsacum.

No endogenous toxins or significant levels of antinutritional factors.

Although some reported cases of maize allergy, protein(s) responsible have not been identified.

Donor Organism Characteristics Expand

Latin Name Gene Pathogenicity
Bacillus thuringiensis subsp. kurstaki cry1Ac

Although target insects are susceptible to oral doses of Bt proteins, there is no evidence of toxic effects in laboratory mammals or bird given up to 10 µg protein / g body wt. There are no significant mammalian toxins or allergens associated with the host organism.

Bacillus thuringiensis var. aizawai cry1F While target insects are susceptible to oral doses of Bt proteins, no evidence of toxic effects in laboratory mammals or birds.
Bacillus thuringiensis cry1Ab

While target insects are susceptible to oral doses of Bt proteins, no evidence of toxic effects in laboratory mammals or birds given up to 10 µg protein/g body weight.

Bacillus thuringiensis cry1Ab

While target insects are susceptible to oral doses of Bt proteins, no evidence of toxic effects in laboratory mammals or birds given up to 10 µg protein/g body weight.

Bacillus thuringiensis subsp. Tenebrionis cry3A While beetles and other coleopterans are susceptible to oral doses of Cry3A protein, there is no evidence of toxic effects in laboratory mammals or birds. There are no significant mammalian toxins or allergens associated with the host organism.
Streptomyces viridochromogenes pat

S. viridochromogenes is ubiquitous in the soil. It exhibits very slight antimicrobial activity, is inhibited by streptomycin, and there have been no reports of adverse affects on humans, animals, or plants.

Streptomyces viridochromogenes pat

S. viridochromogenes is ubiquitous in the soil. It exhibits very slight antimicrobial activity, is inhibited by streptomycin, and there have been no reports of adverse affects on humans, animals, or plants.

Escherichia coli (K-12) hyg

Escherichia coli is one of a number of microorganisms which are normal inhabitants of the colons of virtually all warm-blooded mammals. Ecoli belongs to the taxonomic family known asEnterobacteriaceae, which is one of the best-defined groups of bacteria. The strain Ecoli K-12 is a debilitated strain which does not normally colonize the human intestine. It has also been shown to survive poorly in the environment, has a history of safe commercial use, and is not known to have adverse effects on microorganisms or plants. 

Zea mays epsps

Not applicable.

Modification Method Expand

Coming soon.

Characteristics of the Modification Expand

Coming soon.

Environmental Safety Considerations Expand

Coming soon.

Food and/or Feed Safety Considerations Expand

Coming soon.

Links to Further Information Expand


This record was last modified on Monday, August 8, 2016