Database Product Description
3272 × Bt11 × MIR604 × GA21 (SYN-E3272-5 x SYN-BTØ11-1 x SYN-IR6Ø4-5 x MON-ØØØ21-9)
- Host Organism
- Zea mays (Maize)
- Trait
Insect resistance, coleopteran; insect resistance, lepidoptera; herbicide tolerance, glufosinate; herbicide tolerance, glyphosate; product quality, thermostable alpha-amylase
- Trait Introduction
- Traditional plant breeding and selection
- Proposed Use
Production of maize grain primarily for industrial ethanol.
- Product Developer
- Syngenta Seeds, Inc.
Summary of Regulatory Approvals
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Introduction
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This stacked maize hybrid is a product of traditional plant breeding, and is therefore not automatically subject to regulation in all countries, unlike transgenic plants resulting from recombinant-DNA technologies. The approvals table above does not include entries from these countries. Other countries may request notification in advance of the release of a stacked hybrid, or may request information to conduct an environmental and food safety assessment, and these countries’ decisions are reflected in the approvals table.
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Summary of Introduced Genetic Elements
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| Code |
Name |
Type |
Promoter, other |
Terminator |
Copies |
Form |
|---|
| amy797E |
Alpha-amylase, thermostable |
PQ |
GZein promoter (Zea mays), PEPC9 intron#9 enhancer (Zea mays)
|
35S (Cauliflower mosaic virus)
|
1 |
|
| cry1Ab |
Cry1Ab delta-endotoxin
|
IR |
35S promoter (Cauliflower mosaic virus), IVS6-ADH1 enhancer (Zea mays)
|
NOS terminator (Agrobacterium tumefaciens)
|
1 |
|
| epsps |
5-enolpyruvylshikimate-3-phosphate synthase
|
HT |
Act-1 promoter (Oryza sativa), OTP transit peptide (Helianthus annuus)
|
NOS terminator (Agrobacterium tumefaciens)
|
1 |
|
| mcry3A |
Cry3Aa2 delta endotoxin |
IR |
MTL promoter (Zea mays)
|
NOS terminator (Agrobacterium tumefaciens)
|
1 |
|
| pat |
phosphinotricin acetyltransferase |
HT |
35S promoter (Cauliflower mosaic virus), IVS2-ADH1 enhancer (Zea mays)
|
NOS terminator (Agrobacterium tumefaciens)
|
1 |
|
| pmi |
phosphomannose isomerase |
PQ |
ZmUbiInt promoter (Zea mays)
|
NOS terminator (Agrobacterium tumefaciens)
|
1 |
|
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Characteristics of Zea mays (Maize)
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| Center of Origin |
Reproduction |
Toxins |
Allergenicity |
|---|
Mesoamerican region, now Mexico and Central America
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Cross-pollination via wind-borne pollen is limited, pollen viability is about 30 minutes. Hybridization reported with teosinte species and rarely with members of the genus Tripsacum.
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No endogenous toxins or significant levels of antinutritional factors.
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Although some reported cases of maize allergy, protein(s) responsible have not been identified.
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Donor Organism Characteristics
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| Latin Name |
Gene |
Pathogenicity |
|---|
| Hyperthermophilic microorganisms of the archaeal order Thermococcales |
amy797E |
Thermococcus ssp. are Archaea. They are obligate heterotrophs, growing on organic substrates, usually in the presence of elemental sulphur (S°), which is reduced to hydrogen sulphide. They colonize high-temperature environments. There are no known reports that these organisms adversely affect humans or the environment. |
| Bacillus thuringiensis subsp. kurstaki |
cry1Ac |
Although target insects are susceptible to oral doses of Bt proteins, there is no evidence of toxic effects in laboratory mammals or bird given up to 10 µg protein / g body wt. There are no significant mammalian toxins or allergens associated with the host organism. |
| Zea mays |
epsps |
Not applicable. |
| Bacillus thuringiensis subsp. Tenebrionis |
cry3A |
While beetles and other coleopterans are susceptible to oral doses of Cry3A protein, there is no evidence of toxic effects in laboratory mammals or birds. There are no significant mammalian toxins or allergens associated with the host organism. |
| Streptomyces viridochromogenes |
pat |
S. viridochromogenes is ubiquitous in the soil. It exhibits very slight antimicrobial activity, is inhibited by streptomycin, and there have been no reports of adverse affects on humans, animals, or plants. |
| Escherichia coli (K-12) |
hyg |
Escherichia coli is one of a number of microorganisms which are normal inhabitants of the colons of virtually all warm-blooded mammals. E. coli belongs to the taxonomic family known asEnterobacteriaceae, which is one of the best-defined groups of bacteria. The strain E. coli K-12 is a debilitated strain which does not normally colonize the human intestine. It has also been shown to survive poorly in the environment, has a history of safe commercial use, and is not known to have adverse effects on microorganisms or plants. |
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Modification Method
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Coming soon.
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Characteristics of the Modification
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Coming soon.
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Environmental Safety Considerations
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Coming soon.
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Food and/or Feed Safety Considerations
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Coming soon.
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Links to Further Information
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This record was last modified on Tuesday, March 15, 2016
