GM Crop Database

Database Product Description

3272 × Bt11 × MIR604 × GA21 (SYN-E3272-5 x SYN-BTØ11-1 x SYN-IR6Ø4-5 x MON-ØØØ21-9)
Host Organism
Zea mays (Maize)

Insect resistance, coleopteran; insect resistance, lepidoptera; herbicide tolerance, glufosinate; herbicide tolerance, glyphosate; product quality, thermostable alpha-amylase

Trait Introduction
Traditional plant breeding and selection
Proposed Use

Production of maize grain primarily for industrial ethanol.

Product Developer
Syngenta Seeds, Inc.

Summary of Regulatory Approvals

Country Food Feed Environment Notes
Colombia 2016
Japan 2010 2010 2010
Korea 2013 2012
Mexico 2010 2010
Philippines 2010 2010
Taiwan 2011

Introduction Expand

This stacked maize hybrid is a product of traditional plant breeding, and is therefore not automatically subject to regulation in all countries, unlike transgenic plants resulting from recombinant-DNA technologies. The approvals table above does not include entries from these countries. Other countries may request notification in advance of the release of a stacked hybrid, or may request information to conduct an environmental and food safety assessment, and these countries’ decisions are reflected in the approvals table.

Summary of Introduced Genetic Elements Expand

Code Name Type Promoter, other Terminator Copies Form
amy797E Alpha-amylase, thermostable PQ

GZein promoter (Zea mays), PEPC9 intron#9 enhancer (Zea mays)

35S (Cauliflower mosaic virus)

cry1Ab Cry1Ab delta-endotoxin IR

35S promoter (Cauliflower mosaic virus), IVS6-ADH1 enhancer (Zea mays)

NOS terminator (Agrobacterium tumefaciens)

epsps 5-enolpyruvylshikimate-3-phosphate synthase HT

Act-1 promoter (Oryza sativa), OTP transit peptide (Helianthus annuus)

NOS terminator (Agrobacterium tumefaciens)

mcry3A Cry3Aa2 delta endotoxin IR

MTL promoter (Zea mays)

NOS terminator (Agrobacterium tumefaciens)

pat phosphinotricin acetyltransferase HT

35S promoter (Cauliflower mosaic virus), IVS2-ADH1 enhancer (Zea mays)

NOS terminator (Agrobacterium tumefaciens)

pmi phosphomannose isomerase PQ

ZmUbiInt promoter (Zea mays)

NOS terminator (Agrobacterium tumefaciens)


Characteristics of Zea mays (Maize) Expand

Center of Origin Reproduction Toxins Allergenicity

Mesoamerican region, now Mexico and Central America

Cross-pollination via wind-borne pollen is limited, pollen viability is about 30 minutes. Hybridization reported with teosinte species and rarely with members of the genus Tripsacum.

No endogenous toxins or significant levels of antinutritional factors.

Although some reported cases of maize allergy, protein(s) responsible have not been identified.

Donor Organism Characteristics Expand

Latin Name Gene Pathogenicity
Hyperthermophilic microorganisms of the archaeal order Thermococcales amy797E

Thermococcus ssp. are Archaea. They are obligate heterotrophs, growing on organic substrates, usually in the presence of elemental sulphur (S°), which is reduced to hydrogen sulphide. They colonize high-temperature environments. There are no known reports that these organisms adversely affect humans or the environment.

Bacillus thuringiensis subsp. kurstaki cry1Ac

Although target insects are susceptible to oral doses of Bt proteins, there is no evidence of toxic effects in laboratory mammals or bird given up to 10 µg protein / g body wt. There are no significant mammalian toxins or allergens associated with the host organism.

Zea mays epsps

Not applicable.

Bacillus thuringiensis subsp. Tenebrionis cry3A While beetles and other coleopterans are susceptible to oral doses of Cry3A protein, there is no evidence of toxic effects in laboratory mammals or birds. There are no significant mammalian toxins or allergens associated with the host organism.
Streptomyces viridochromogenes pat

S. viridochromogenes is ubiquitous in the soil. It exhibits very slight antimicrobial activity, is inhibited by streptomycin, and there have been no reports of adverse affects on humans, animals, or plants.

Escherichia coli (K-12) hyg

Escherichia coli is one of a number of microorganisms which are normal inhabitants of the colons of virtually all warm-blooded mammals. Ecoli belongs to the taxonomic family known asEnterobacteriaceae, which is one of the best-defined groups of bacteria. The strain Ecoli K-12 is a debilitated strain which does not normally colonize the human intestine. It has also been shown to survive poorly in the environment, has a history of safe commercial use, and is not known to have adverse effects on microorganisms or plants. 

Modification Method Expand

Coming soon.

Characteristics of the Modification Expand

Coming soon.

Environmental Safety Considerations Expand

Coming soon.

Food and/or Feed Safety Considerations Expand

Coming soon.

Links to Further Information Expand

This record was last modified on Friday, August 4, 2017